AP

Pfizer study suggests vaccine works against virus variant

Jan 8, 2021, 6:04 AM
Utah vaccines...
The Davis County Health Department will begin administering COVID-19 vaccines to residents 70-years-old and above starting Tuesday. It comes following some early issues with getting people signed up. (AP Photo/Jae C. Hong)
(AP Photo/Jae C. Hong)

New research suggests that Pfizer’s COVID-19 vaccine can protect against a mutation found in two highly contagious variants of the coronavirus that erupted in Britain and South Africa.

Those variants are causing global concern. They both share a common mutation called N501Y, a slight alteration on one spot of the spike protein that coats the virus. That change is believed to be the reason they can spread so easily.

Most of the vaccines being rolled out around the world train the body to recognize that spike protein and fight it. Pfizer teamed with researchers from the University of Texas Medical Branch in Galveston for laboratory tests to see if the mutation affected its vaccine’s ability to do so.

They used blood samples from 20 people who received the vaccine, made by Pfizer and its German partner BioNTech, during a large study of the shots. Antibodies from those vaccine recipients successfully fended off the virus in lab dishes, according to the study posted late Thursday on an online site for researchers.

The study is preliminary and has not yet been reviewed by experts, a key step for medical research.

But “it was a very reassuring finding that at least this mutation, which was one of the ones people are most concerned about, does not seem to be a problem” for the vaccine, said Pfizer chief scientific officer Dr. Philip Dormitzer.

Viruses constantly undergo minor changes as they spread from person to person. Scientists have used these slight modifications to track how the coronavirus has moved around the globe since it was first detected in China about a year ago.

British scientists have said the variant found in the U.K. – which has become the dominant type in parts of England — still seemed to be susceptible to vaccines. That mutant has now been found in the U.S. and numerous other countries.

But the variant first discovered in South Africa has an additional mutation that has scientists on edge, one named E484K.

The Pfizer study found that the vaccine appeared to work against 15 additional possible virus mutations, but E484K wasn’t among those tested. Dormitzer said it is next on the list.

Dr. Anthony Fauci, the top U.S. infectious disease expert, recently said vaccines are designed to recognize multiple parts of the spike protein, making it unlikely a single mutation could be enough to block them. But scientists around the world are conducting research with different vaccines to find out.

Dormitzer said if the virus eventually mutates enough that the vaccine needs adjusting – much like flu shots are adjusted most years – that tweaking the recipe wouldn’t be difficult for his company’s shot and similar ones. The vaccine is made with a piece of the virus genetic code, simple to switch, although it’s not clear what kind of additional testing regulators would require to make such a change.

Dormitzer said this was only the beginning “of ongoing monitoring of virus changes to see if any of them might impact on vaccine coverage.”

____

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.


How To Prevent the Spread of COVID-19 Coronavirus

COVID-19 coronaviruses transmitted from person to person. It is a virus that is similar to the common cold and the flu. So, to prevent it from spreading:

  • Wash hands frequently and thoroughly, with soap and water, for at least 20 seconds.
  • Wear a mask.
  • Don’t touch your face.
  • Keep children and those with compromised immune systems away from someone who is coughing or sneezing (in this instance, at least six feet)
  • If there is an outbreak near you, practice social distancing (stay at home, instead of going to the movies, sports events, or other activities.)
  • Get a flu shot.

Local resources

KSL Coronavirus Q&A

Utah’s Coronavirus Information

Utah State Board of Education

Utah Hospital Association

The Church of Jesus Christ of Latter-day Saints

Utah Coronavirus Information Line – 1-800-456-7707

National Resources

Centers for Disease Control and Prevention

Commonly asked questions, World Health Organization

Cases in the United States

 

We want to hear from you.

Have a story idea or tip? Send it to the KSL NewsRadio team here.

Today’s Top Stories

AP

A woman sits on the rubble as emergency rescue teams search for people under the remains of destroy...
MEHMET GUZEL, GHAITH ALSAYED and SUZAN FRASER

Race to find survivors as earthquake aid pours into Turkey, Syria

The death toll has risen to above 5,300. Monday's quake and strong aftershocks hit hundreds of kilometers across southeastern Turkey and neighboring Syria.
1 day ago
quit their jobs...
PAUL WISEMAN AP Economics Writer

US added a strong 517,000 jobs in January despite Fed hikes

The Fed is aiming to achieve a "soft landing" — a pullback in the economy that is enough to tame high inflation without triggering recession.
5 days ago
Thousands of fraudulent nursing diplomas  were dispersed in Florida. (Canva)...
Associated Press via Miami Herald

Fake nursing diploma scheme in Florida; 25 arrested

The defendants each face up to 20 years in prison.
6 days ago
Microsoft is cutting 10,000 workers, almost 5% of its workforce, in response to "macroeconomic cond...
MATT O'BRIEN, Associated Press

Job cuts in tech sector spread, Microsoft lays off 10,000

Microsoft said in a regulatory filing Wednesday that had just notified employees of the layoffs, some of which begin immediately.
21 days ago
exxon mobil sign pictured...
SETH BORENSTEIN and CATHY BUSSEWITZ Associated Press

Study: Exxon Mobil accurately predicted warming since 1970s

Exxon said its understanding of climate change evolved over the years and that critics are misunderstanding its earlier research.
27 days ago
FILE - Protesters, supporters of Brazil's former President Jair Bolsonaro, stand on the roof of the...
The Associated Press

Brazil and Jan. 6 in US: Parallel attacks, but not identical

RIO DE JANIERO, Brazil — Enraged protesters broke into government buildings that are the very symbol of their country’s democracy. Driven by conspiracy theories about their candidate’s loss in the last election, they smashed windows, sifted through the desks of lawmakers and trashed the highest offices in the land in a rampage that lasted hours […]
29 days ago

Sponsored Articles

Skier being towed by a rider on a horse. Skijoring....
Bear Lake Convention and Visitors Bureau

Looking for a New Winter Activity? Try Skijoring in Bear Lake

This article about skijoring is sponsored by the Bear Lake Convention & Visitors Bureau. Participate in Skijoring the Bear on February 20th, 2023.  What is skijoring? Skijoring is when someone on skis is pulled by a horse, dog, animal, or motor vehicle. The driver leads the skiers through an obstacle course over jumps, hoops, and […]
Banner with Cervical Cancer Awareness Realistic Ribbon...
Intermountain Health

Five Common Causes of Cervical Cancer – and What You Can Do to Lower Your Risk

January is National Cervical Cancer Awareness month and cancer experts at Intermountain Health are working to educate women about cervical cancer, the tests that can warn women about potential cancer, and the importance of vaccination.
Kid holding a cisco fish at winterfest...
Bear Lake Convention and Visitors Bureau

Get Ready for Fun at the 2023 Bear Lake Monster Winterfest

The Bear Lake Monster Winterfest is an annual weekend event jam-packed full of fun activities the whole family can enjoy. This year the event will be held from January 27-29 at the Utah Bear Lake State Park Marina and Sunrise Resort and Event Center in Garden City, Utah. 
happy friends with sparklers at christmas dinner...
Macey's

15 Easy Christmas Dinner Ideas

We’ve scoured the web for you and narrowed down a few of our favorite Christmas dinner ideas to make your planning easy. Choose from the dishes we’ve highlighted to plan your meal or start brainstorming your own meal plan a couple of weeks before to make sure you have time to shop and prepare.
Spicy Homemade Loaded Taters Tots...
Macey's

5 Game Day Snacks for the Whole Family (with recipes!)

Try these game day snacks to make watching football at home with your family feel like a special occasion. 
Happy joyful smiling casual satisfied woman learning and communicates in sign language online using...
Sorenson

The Best Tools for Deaf and Hard-of-Hearing Workplace Success

Here are some of the best resources to make your workplace work better for Deaf and hard-of-hearing employees.
Pfizer study suggests vaccine works against virus variant