What to know about the Bundibugyo virus, a species of Ebola causing an outbreak in Congo

The virus causing an outbreak in Congo suspected of killing more than 130 people is less common than others that cause Ebola disease, which is complicating the response because there are no specific treatments or vaccines.

“There’s nothing even close to ready for clinical trials,” said Dr. Celine Gounder, an infectious disease specialist and epidemiologist who treated patients in West Africa during the 2014-2016 Ebola epidemic. “And so that means responders, healthcare workers and other aid workers are really back to the basics.”

Dr. Vasee Moorthy, a special adviser in the office of the WHO chief scientist, said the most promising candidate vaccine to address Bundibugyo would not be available for at least six to nine months.

Here’s what to know about Bundibugyo virus, the rare species behind the outbreak.

Bundibugyo virus has caused two other outbreaks

Bundibugyo virus has caused two other outbreaks, all in the same region of the Congo River basin, said Dr. Tom Ksiazek, a University of Texas Medical Branch virologist and veterinarian. He directed the U.S. Centers for Disease Control and Prevention’s Special Pathogens Branch, which first identified the virus in 2007.

Other viruses that cause Ebola disease are the Ebola virus (sometimes called the Zaire virus), the Sudan virus, and the Taï Forest virus, which is not known to cause large outbreaks.

How Bundibugyo virus is spread

The virus is spread through close contact with sick or deceased patients’ bodily fluids, such as sweat, blood, feces or vomit. Healthcare workers and family members caring for sick patients face the highest risk, experts said.

“So very often we see doctors and nurses among the first to be infected and to die,” said Gounder, editor-at-large for public health at KFF Health News.

Bundibugyo may be less lethal, but still extremely dangerous

From the few outbreaks health experts have seen, Bundibugyo might be slightly less deadly than Ebola virus or Sudan virus.

“I think a 30%-plus mortality rate is still quite scary, but it’s hard to say with a lot of precision because we don’t have a lot of experience,” Gounder said.

How to care for patients if there are no treatments or vaccines

In the other two Bundibugyo outbreaks, initial cases were identified early, Ksiazek said, allowing for a quick public health response: getting healthcare workers proper protective equipment, finding and isolating people who were exposed and offering supportive medical care to patients. Proper medical care “reduces mortality significantly,” he said.

That includes giving patients lots of IV or oral fluids, Gounder said.

How public health workers are trying to contain the outbreak

Health workers are now working to find and isolate cases, trace their contacts and educate people about how to avoid the virus. In the West African Ebola epidemic, ensuring safe methods of burial was key to stopping the spread, said Gounder, because people were getting sick from preparing their loved ones’ bodies for funeral rites. Making sure health workers have proper protective equipment is also critical, experts said.

“Of course, it’s problematic because vaccines are some of our best tools for combating infectious diseases,” said Lina Moses, an epidemiologist and disease ecologist at Tulane University. But other public health tools — public education, contact tracing, quick testing — still work, she said.

“It’s important to keep in mind that every single Ebola outbreak that has occurred in the (Democratic Republic of the Congo) — we’re on our 17th now — has been stopped,” she said.
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Associated Press writers Mogomotsi Magome in Johannesburg and Jamey Keaten in Geneva contributed.
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